|本期目录/Table of Contents|

依维莫司相关间质性肺病研究进展

《现代肿瘤医学》[ISSN:1672-4992/CN:61-1415/R]

期数:
2019年20期
页码:
3743-3745
栏目:
综述
出版日期:
2019-09-08

文章信息/Info

Title:
Research progress on the everolimus-related interstitial lung disease
作者:
王 娟1;?张甜甜2;?张朝阳3;?钟春生1
1.蚌埠医学院附属蚌埠市第三人民医院肿瘤内科,安徽 蚌埠 233000;2.蚌埠医学院第一附属医院肿瘤内科;3.肿瘤外科,安徽 蚌埠 233004
Author(s):
Wang Juan1;?Zhang Tiantian2;?Zhang Chaoyang3;?Zhong Chunsheng1
1.Department of Medical Oncology,the Third People's Hospital of Bengbu,Affiliated to Bengbu Medical College,Anhui Bengbu 233000,China;2.Department of Medical Oncology;3.Department of Surgical Oncology,the First Affiliated Hospital of Bengbu Medical College,Anhui Bengbu 233004,China.
关键词:
依维莫司;?哺乳动物雷帕霉素靶点(mTOR)抑制剂;?间质性肺病
Keywords:
everolimus;?mammalian target of rapamycin (mTOR) inhibitor;?interstitial lung disease
分类号:
R730.5
DOI:
10.3969/j.issn.1672-4992.2019.20.045
文献标识码:
A
qq自动领红包软件:
依维莫司是一种哺乳动物雷帕霉素靶点(mammalian target of rapamycin,mTOR)抑制剂,目前已被FDA获批用于肾癌、乳腺癌、胃癌、胰腺癌、神经内分泌癌等的晚期维持治疗,能显着改善患者预后,但常伴发不良反应的产生。间质性肺病是依维莫司常见的不良反应之一,具有死亡率高、诊断困难等特点,限制了依维莫司在临床上的应用。因此,正确地诊断和治疗依维莫司相关性肺病至关重要。
Abstract:
Everolimus is a mammalian target of rapamycin (mTOR) inhibitor that has been approved by the FDA for advanced maintenance therapy for kidney cancer,breast cancer,gastric cancer,pancreatic cancer and neuroendocrine cancer.It can significantly improve the prognosis of patients,but certain adverse reactions were often accompanied.Interstitial lung disease is one of the common adverse reactions to everolimus.Its high mortality rate and difficulty in diagnosis limit the clinical application of everolimus.Therefore,correct diagnosis and treatment of everolimus-related lung disease is essential.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 1900-01-01