|本期目录/Table of Contents|

miR-590在恶性肿瘤中的研究进展

《现代肿瘤医学》[ISSN:1672-4992/CN:61-1415/R]

期数:
2019年20期
页码:
3702-3705
栏目:
综述
出版日期:
2019-09-08

文章信息/Info

Title:
Research progress of miR-590 in malignant tumor
作者:
王书廷;?李高峰;?李 恒;?吴安皓
昆明医科大学第三附属医院暨云南省肿瘤医院胸外二科,云南 昆明 650100
Author(s):
Wang Shuting;?Li Gaofeng;?Li Heng;?Wu Anhao
Department of Thoracic Surgery,the Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital,Yunnan Kunming 650100,China.
关键词:
微小RNA;?miR-590;?肿瘤;?治疗靶点
Keywords:
microRNA;?miR-590;?tumor;?therapeutic target
分类号:
R730
DOI:
10.3969/j.issn.1672-4992.2019.20.035
文献标识码:
A
qq自动领红包软件:
微小RNA(microRNA,miRNA,miR)是一类小的单链非编码RNA,长度为18~25个核苷酸,通过与mRNA的3' 非翻译区(3' untranslated region,3' UTR)中不完全匹配的序列来沉默基因表达,具有高度保守的序列。越来越多的研究已经在各种类型的恶性肿瘤中观察到miRNA,并且发现miRNA参与调节癌细胞行为,包括细胞增殖、凋亡、迁移和侵袭。miR-590的表达和功能在不同类型的肿瘤中并不相同,其表达的失调与恶性肿瘤的发生发展、治疗及预后密切相关。本文就miR-590在各种恶性肿瘤中的最新研究进展作一综述。
Abstract:
MicroRNAs (miRNAs,miRs) are small,single-stranded,non-coding RNAs that are 18~25 nucleotides in length and silenced by sequences that do not exactly match the 3' untranslated region (3' UTR) of mRNA,with highly conserved sequences.A growing body of research has observed miRNAs in various types of malignancies and found that miRNAs are involved in the regulation of cancer cell behavior,including cell proliferation,apoptosis,migration and invasion.The expression and function of miR-590 are not the same in different types of tumors,and the dysregulation of expression is closely related to the occurrence,development,treatment and prognosis of malignant tumor.This article reviews the recent progresses on miR-590 in various malignancies.

参考文献/References

[1]Al-Eryani L,SF Jenkins,VA States,et al.miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions[J].PLoS One,2018,13(8):e0202579.
[2]Bartel DP.MicroRNAs:Target recognition and regulatory functions[J].Cell,2009,136(2):215-233.
[3]Zhang X,Li Y,Qi P,et al.Biology of miR-17-92 cluster and its progress in lung cancer[J].Int J Med Sci,2018,15(13):1443-1448.
[4]Tong Q,Zhu Y,Zhang D,et al.MicroRNA quantitation during dendritic cell endocytosis using imaging flow cytometry:Key factors and requirements[J].Cell Physiol Biochem,2018,51(2):793-811.
[5]Xiao X,Tang C,Xiao S,et al.Enhancement of proliferation and invasion by microRNA-590-5p via targeting PBRM1 in clear cell renal carcinoma cells[J].Oncol Res,2013,20(11):537-544.
[6]Wang L,Wei WQ,Wu ZY,et al.MicroRNA-590-5p regulates cell viability,apoptosis,migration and invasion of renal cell carcinoma cell lines through targeting ARHGAP24[J].Mol Biosyst,2017,13(12):2564-2573.
[7]Chiantore MV,Mangino G,Iuliano M,et al.Human papillomavirus E6 and E7 oncoproteins affect the expression of cancer-related microRNAs:Additional evidence in HPV-induced tumorigenesis[J].J Cancer Res Clin Oncol,2016,142(8):1751-1763.
[8]Miranda PJ,Vimalraj S,Selvamurugan N.A feedback expression of microRNA-590 and activating transcription factor-3 in human breast cancer cells[J].Int J Biol Macromol,2015(72):145-150.
[9]Yang X,Wu X.miRNA expression profile of vulvar squamous cell carcinoma and identification of the oncogenic role of miR-590-5p[J].Oncol Rep,2016,35(1):398-408.
[10]Gu L,Lu LS,Zhou DL,et al.UCA1 promotes cell proliferation and invasion of gastric cancer by targeting CREB1 sponging to miR-590-3p[J].Cancer Med,2018,7(4):1253-1263.
[11]Bray F,Ferlay J,Soerjomataram I,et al.Global cancer statistics 2018:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer J Clin,2018,68(6):394-424.
[12]Zhou L,Zhao LC,Jiang N,et al.MicroRNA miR-590-5p inhibits breast cancer cell stemness and metastasis by targeting SOX2[J].Eur Rev Med Pharmacol Sci,2017,21(1):87-94.
[13]Sheikholeslami A,Nabiuni M,Arefian E.Suppressing the molecular signaling pathways involved in inflammation and cancer in breast cancer cell lines MDA-MB-231 and MCF-7 by miR-590[J].Tumour Biol,2017,39(4):1010428317697570.
[14]Gao J,Yu SR,Yuan Y,et al.MicroRNA-590-5p functions as a tumor suppressor in breast cancer conferring inhibitory effects on cell migration,invasion,and epithelial-mesenchymal transition by downregulating the Wnt-beta-catenin signaling pathway[J].J Cell Physiol,2019,234(2):1827-1841.
[15]Rohini M,Gokulnath M,Miranda PJ,et al.miR-590-3p inhibits proliferation and promotes apoptosis by targeting activating transcription factor 3 in human breast cancer cells[J].Biochimie,2018(154):10-18.
[16]Song Q,Chen Q,Wang Q,et al.ATF-3/miR-590/GOLPH3 signaling pathway regulates proliferation of breast cancer[J].BMC Cancer,2018,18(1):255.
[17]Chu Y,Ouyang Y,Wang F,et al.MicroRNA-590 promotes cervical cancer cell growth and invasion by targeting CHL1[J].J Cell Biochem,2014,115(5):847-853.
[18]Dong BS,Shi MJ,Su SB,et al.Insight into long noncoding competing endogenous RNA networks in hepatic fibrosis:The potential implications for mechanism and therapy[J].Gene,2018(687):255-260.
[19]Huo H,Tian J,Wang R,et al.Long non-coding RNA NORAD upregulate SIP1 expression to promote cell proliferation and invasion in cervical cancer[J].Biomed Pharmacother,2018(106):1454-1460.
[20]Salem M,O' Brien JA,Bernaudo S,et al.miR-590-3p promotes ovarian cancer growth and metastasis via a novel FOXA2-versican pathway[J].Cancer Res,2018,78(15):4175-4190.
[21]Ma Z,Wang Y,He B,et al.Expression of miR-590 in lung cancer and its correlation with prognosis[J].Oncol Lett,2018,15(2):1753-1757.
[22]Wang X,Yin H,Zhang H,et al.NF-kappaB-driven improvement of EHD1 contributes to erlotinib resistance in EGFR-mutant lung cancers[J].Cell Death Dis,2018,9(4):418.
[23]Xu L,Li T,Ding W,et al.Combined seven miRNAs for early hepatocellular carcinoma detection with chronic low-dose exposure to microcystin-LR in mice[J].Sci Total Environ,2018(628-629):271-281.
[24]Yang H,Zheng W,Zhao W,et al.Roles of miR-590-5p and miR-590-3p in the development of hepatocellular carcinoma[J].Journal of Southern Medical University,2013,33(6):804-811.
[25]He B,Lu P,Guan L,et al.Identifying key regulating miRNAs in hepatocellular carcinomas by an omics' method[J].Oncotarget,2017,8(61):103919-103930.
[26]Sui J,Yang X,Qi W,et al.Long non-coding RNA linc-USP16 functions as a tumour suppressor in hepatocellular carcinoma by regulating PTEN expression[J].Cell Physiol Biochem,2017,44(3):1188-1198.
[27]Chen M,Wu L,Tu J,et al.miR-590-5p suppresses hepatocellular carcinoma chemoresistance by targeting YAP1 expression[J].EBioMedicine,2018(35):142-154.
[28]Mou K,Ding M,Han D,et al.miR-590-5p inhibits tumor growth in malignant melanoma by suppressing YAP1 expression[J].Oncol Rep,2018,40(4):2056-2066.
[29]Mou K,Liu B,Ding M,et al.lncRNA-ATB functions as a competing endogenous RNA to promote YAP1 by sponging miR-590-5p in malignant melanoma[J].Int J Oncol,2018,53(3):1094-1104.
[30]Zhang J,Jin M,Chen X,et al.Loss of PPM1F expression predicts tumour recurrence and is negatively regulated by miR-590-3p in gastric cancer[J].Cell Prolif,2018,51(4):e12444.
[31]Wang Y,Xu X,Maglic D,et al.Comprehensive molecular characterization of the Hippo signaling pathway in cancer[J].Cell Rep,2018,25(5):1304-1317.e5.
[32]Kim CW,Oh ET,Kim JM,et al.Hypoxia-induced microRNA-590-5p promotes colorectal cancer progression by modulating matrix metalloproteinase activity[J].Cancer Lett,2018(416):31-41.
[33]Cai W,Xu Y,Yin J,et al.miR-590-5p suppresses osteosarcoma cell proliferation and invasion via targeting KLF5[J].Mol Med Rep,2018,18(2):2328-2334.
[34]Hu R,Zhu X,Chen C,et al.RNA-binding protein PUM2 suppresses osteosarcoma progression via partly and competitively binding to STARD13 3' UTR with miRNAs[J].Cell Prolif,2018,51(6):e12508.
[35]Di Agostino,Valenti SF,Sacconi A,et al.Long non-coding MIR205HG depletes hsa-miR-590-3p leading to unrestrained proliferation in head and neck squamous cell carcinoma[J].Theranostics,2018,8(7):1850-1868.
[36]Miao MH,Ji XQ,Zhang H,et al.miR-590 promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia by inhibiting RB1[J].Oncotarget,2016,7(26):39527-39534.

备注/Memo

备注/Memo:
National Natural Science Foundation of China(No.81760554,81460356);国家自然科学基金资助项目(编号:81760554,81460356)
更新日期/Last Update: 1900-01-01